The File - Page Setup command allows us to set paper orientation (portrait or landscape), paper size, printer, printer properties and margins. Page setup options will be applied to any print job and will be automatically incorporated into Layouts that may be created.
The Page Setup dialog uses inches or millimeters depending on the setting of the Use English Measurement Units checkbox in the Tools - Options dialog.
Some multipage layouts of large maps using white backgrounds may result in some pages with no printing on them because the page falls entirely within a "whitespace" area of the map. By default, all pages are printed, even blank pages. To save paper, we can uncheck Print blank pages in multipage printouts in Tools - Options - User Interface.